Despite impressive reductions in the newborn mortality rate (NMR) across the globe, advances are not equal among countries. A Lives Saved analysis revealed the impact of inpatient care of small and sick newborns (SSNBs) to be the biggest in averting newborn mortality. Yet, 80% of the 30 million newborns that require inpatient care each year do not receive it. To address this critical gap, the Every Newborn Action Plan added a fourth target on SSNBs for countries to achieve by 2025: 80% of countries have a national implementation plan for SSNB care and 80% of districts have a functional level-2 in-patient unit to care for SSNBs with respiratory support, including continuous positive airway pressure (CPAP). To guide countries' efforts towards achieving this target, the World Health Organization (WHO) and United Nations Children's Fund (UNICEF) have developed standards for improving the quality of care for SSNBs in health facilities and a model of level-2 care.This session will bring together global and country partners to discuss the global guidance and country implementation of SSNB care. The panel will begin with parents who will share their experience as partners caring for their hospitalized newborns. UNICEF will describe the SSNB model of care and share key insights on scale. A moderated panel discussion will follow, with government officials from Bangladesh, Nepal, Rwanda, Sierra Leone, and Tanzania to delve into components of country-contextualized models of SSNB care and learn from experiences in organizing systems scale-up of services.