Prevention and Clinical Management | Targets and Metrics | Strengthening Quality of Care | Focus: Small and Sick Newborns | Focus: Private Sector Room: 1.63-1.64 Oral Abstracts
May 10, 2023 11:50 - 13:05(Africa/Johannesburg)
20230510T1150 20230510T1305 Africa/Johannesburg Neonatal Respiratory Distress Syndrome: Understanding the Drivers, Optimizing the Tools

Outborn Newborns Drive Birth Asphyxia Mortality Rates: A Nine-Year Analysis at a Rural Level 2 Nursery in Uganda

Birth asphyxia is a leading cause of global neonatal mortality, with the vast majority of cases in low- and middle- income countries. While the global death rate from asphyxia has decreased over the last 30 years, it is increasing in Uganda and makes up half of neonatal deaths. Improved understanding of the risk factors associated with mortality among these patients is needed.

Barriers Limiting Access to Caffeine for Preterm Infants with Apnea of Prematurity in Low- and Middle-Income Countries (LMICs): Findings from a Landscaping Conducted in Nigeria, Ethiopia, Kenya, South Africa, and India 

Every year, 15 million babies are born preterm. Preterm complications are the leading cause of death among children under five years of age, and responsible for one million deaths in 2015. A driver of premature deaths is apnea of prematurity (AOP), which is the cessation of breathing lasting more than 15 seconds. A drug, caffeine citrate, listed in the World Health Organization (WHO) Essential Medicines List (EML) and recommended as a drug of choice in neonatal guidelines, can prevent and treat AOP. While caffeine is the mainstay of prevention and treatment in high-income countries, it is not widely used in low-income countries, where more preterm deaths occur. An alternative, Aminophylline, is more commonly used in low- and middle-income countries (LMICs) even though evidence shows that caffeine has a better side effect profile, lower toxicity, and requires less monitoring.

Bubble Continuous Positive Airway Pressure (CPAP) with a Blender (Vayu) Is Associated with Immediate Improvement in Physiologic and Clinical Parameters 

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Room: 1.63-1.64 International Maternal Newborn Health Conference 2023 information@imnhc.org
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Outborn Newborns Drive Birth Asphyxia Mortality Rates: A Nine-Year Analysis at a Rural Level 2 Nursery in Uganda

Birth asphyxia is a leading cause of global neonatal mortality, with the vast majority of cases in low- and middle- income countries. While the global death rate from asphyxia has decreased over the last 30 years, it is increasing in Uganda and makes up half of neonatal deaths. Improved understanding of the risk factors associated with mortality among these patients is needed.


Barriers Limiting Access to Caffeine for Preterm Infants with Apnea of Prematurity in Low- and Middle-Income Countries (LMICs): Findings from a Landscaping Conducted in Nigeria, Ethiopia, Kenya, South Africa, and India 

Every year, 15 million babies are born preterm. Preterm complications are the leading cause of death among children under five years of age, and responsible for one million deaths in 2015. A driver of premature deaths is apnea of prematurity (AOP), which is the cessation of breathing lasting more than 15 seconds. A drug, caffeine citrate, listed in the World Health Organization (WHO) Essential Medicines List (EML) and recommended as a drug of choice in neonatal guidelines, can prevent and treat AOP. While caffeine is the mainstay of prevention and treatment in high-income countries, it is not widely used in low-income countries, where more preterm deaths occur. An alternative, Aminophylline, is more commonly used in low- and middle-income countries (LMICs) even though evidence shows that caffeine has a better side effect profile, lower toxicity, and requires less monitoring.


Bubble Continuous Positive Airway Pressure (CPAP) with a Blender (Vayu) Is Associated with Immediate Improvement in Physiologic and Clinical Parameters 

Respiratory distress syndrome (RDS) often complicates the clinical course of premature infants less than 2,000 grams, with progressive respiratory failure if untreated. Continuous positive airway pressure (CPAP) has been shown to modulate the clinical course. A novel compact bubble CPAP system with an ambient/oxygen blender developed by Vayu has the potential to modify the course of RDS. The objective was to determine whether use of Vayu CPAP will be associated with improvement in physiologic and clinical parameters, i.e., heart rate (HR), O2 saturation, FiO2 requirement, respiratory rate (RR), respiratory distress assessed by Silverman score (SS), and whether it modifies the clinical course of premature infants with RDS.


Immediate Skin-to-Skin Contact May Have Beneficial Effects on the Cardiorespiratory Stabilisation in Very Preterm Infants 

The transition from foetal to newborn life is a period of rapid physiological change. The first hour of life is referred to as the golden hour, because initial strategies in newborn care may lead to a better start to life and subsequently optimal long-term health and development. Preterm newborns are typically cared for in incubators in the immediate period following birth. It is suggested that mother-infant regulation of physiological systems is desirable immediately after birth.

Outborn Newborns Drive Birth Asphyxia Mortality Rates: A Nine-Year Analysis at a Rural Level 2 Nursery in Uganda
Single Abstract 11:50 AM - 01:05 PM (Africa/Johannesburg) 2023/05/10 09:50:00 UTC - 2023/05/10 11:05:00 UTC
Small and Sick Newborns (SSNB)
Targets and Metrics
Prevention and Clinical Management
Presenters James Nyonyintono
Clinical Programs Manager, Kiwoko Hospital
Co-authors Anna Hedstrom
Associate Professor, University Of Washington
PM
Paul Mubiri
Research Fellow, Makerere University School Of Public Health
HN
Harriet Nambuya
Paediatrician, Jinja Regional Referral Hospital
JN
Josephine Nakakande
Registered Nurse, NICU , Kiwoko Hospital
HN
Hilda Namakula
Clinical Educator, Adara Development
Brooke Magnusson
Global Health Director, Adara Development
Molly MacGuffie
Clinical Programmes Manager, Nurse, Adara Development
MN
Mushin Nsubuga
OBGYN , Kiwoko Hospital
Peter Waiswa
Professor, Makerere University
Maneesh Batra
Neonatologist, Professor, University Of Washington Departments Of Pediatrics And Global Health
Barriers Limiting Access to Caffeine for Preterm Infants with Apnea of Prematurity in Low- and Middle-Income Countries (LMICs): Findings from a Landscaping Conducted in Nigeria, Ethiopia, Kenya, South Africa, and India
Single Abstract 11:50 AM - 01:05 PM (Africa/Johannesburg) 2023/05/10 09:50:00 UTC - 2023/05/10 11:05:00 UTC
Small and Sick Newborns (SSNB), Private Sector
Strengthening Quality of Care
Prevention and Clinical Management
Presenters Oluwaseun Aladesanmi
Associate Program Director, Maternal Newborn Health, Clinton Health Access Initiative
Co-authors Andrew Storey
Senior Director, Maternal And Newborn Health, Clinton Health Access Initiative
RF
Ryan Fu
Director, Global Markets Team, Clinton Health Access Initiative
ZD
Zelalem Demeke
Senior Program Manager , Clinton Health Access Initiative
IA
Isa Adamu
Analyst, Neglected Diseases , Clinton Health Access Initiative
BW
Betty Wariari
Associate Director -MNCH, Clinton Health Access Initiative
MS
Mansharan Seth
Deputy Director, Nutrition, Clinton Health Access Initiative
UB
Unathi Beku
Associate, Maternal And Neonatal Health, Clinton Health Access Initiative
HM
Hema Magge
Senior Program Officer, Newborn Health, Bill And Melinda Gates Foundation
AC
Amanda Cafaro
Senior Program Officer, BMGF
Bubble Continuous Positive Airway Pressure (CPAP) with a Blender (Vayu) Is Associated with Immediate Improvement in Physiologic and Clinical Parameters
Single Abstract 11:50 AM - 01:05 PM (Africa/Johannesburg) 2023/05/10 09:50:00 UTC - 2023/05/10 11:05:00 UTC
Small and Sick Newborns (SSNB)
Prevention and Clinical Management
Prevention and Clinical Management
Presenters
EA
Emily Ahn
Neonatal Fellow, New York Presbytrian Hospital
JP
Jeffrey Perlman
Professor Of Pediatrics, Weill Cornell Medicine
Co-authors
MM
Mathew Mselle
Pediatric Resident, KIlmanjaro Medical Cnter Hospital
AS
Aisa Shayo
Chair Of Pediatrics, Kilmanjaro Christian Medical University
AS
Anna Sechu
Head Nursing, Neonatal Area, Kilimanjaro Christian Medical Center
Immediate Skin-to-Skin Contact May Have Beneficial Effects on the Cardiorespiratory Stabilisation in Very Preterm Infants
Single Abstract 11:50 AM - 01:05 PM (Africa/Johannesburg) 2023/05/10 09:50:00 UTC - 2023/05/10 11:05:00 UTC
Small and Sick Newborns (SSNB)
Strengthening Quality of Care
Prevention and Clinical Management
Presenters
KL
Karoline Lode
Co-authors Agnes Linnér
Neonatologist, Postdoctoral Researcher, Karolinska Institutet
SK
Stina Klemming
Dr, Lund University Hospital
NB
Nils Bergman
Neonatologist, Karolinska Institutet
SL
Siri Lilliesköld
Specialist Nurse, Department Of Women’s And Children’s Health, Karolinska Institutet, Stockholm
HM
Hanne Markhus Pike
Pediatrician, Department Of Paediatrics, Stavanger University Hospital, Stavanger
BW
Björn Westrup
Senior Consultant In Neonatology, Department Of Women’s And Children’s Health, Karolinska Institutet, Stockholm
SR
Siren Rettedal
Neonatologist, Professor, Stavanger University Hospital
WJ
Wibke Jonas
Assistant Professor, Department Of Women’s And Children’s Health, Karolinska Institutet, Stockholm, Sweden
Neonatal Fellow
,
New York Presbytrian Hospital
Associate Program Director, Maternal Newborn Health
,
Clinton Health Access Initiative
Clinical Programs Manager
,
Kiwoko Hospital
Dr. Neena Khadka Basnet
Newborn Health Focal Point
,
MOMENTUM Country and Global Leadership / Save the Children USA
Mr. Nitesh Kumar Jangir
Director and Co-Founder
,
InnAccel Technologies Pvt. Ltd.
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