Humanitarian and Fragile Settings | Prevention and Clinical Management | Health Systems and Workforce | Strengthening Quality of Care | Focus: COVID-19 | Focus: Small and Sick Newborns Room: 1.43-1.44 Oral Abstracts
May 10, 2023 09:10 - 10:25(Africa/Johannesburg)
20230510T0910 20230510T1025 Africa/Johannesburg Determinants of Maternal and Newborn Infections and Related Outcomes

Mycoplasma Genitalium and Other Reproductive Tract Infections in Pregnancy Associated with an Increased Risk of Adverse Birth Outcomes in a High-Burden Setting

Being born too small is a major risk factor for neonatal and infant mortality and childhood stunting. Sexually transmitted infections (STIs) are preventable and curable infections that can contribute to poor pregnancy outcomes. Mycoplasma genitalium is increasingly recognized as an STI with high prevalence in some populations and has a high propensity to develop antimicrobial resistance. Little data are available on the impact of M. genitalium on adverse birth outcomes, particularly in the context of other STIs. In Papua New Guinea (PNG), we previously demonstrated a high burden of multiple STIs (M. genitalium, Chlamydia trachomatis, Neisseria gonorrhoeae, Trichomonas vaginalis, and bacterial vaginosis [BV]). Here, we have investigated the association between M. genitalium and other STIs and birthweight, preterm birth, and perinatal mortality.

The Clinical Presentation and Detection of Tuberculosis during Pregnancy and in the Postpartum Period in Low- and Middle-Income Countries: A Systematic Review and Meta-analysis 

For women infected with Mycobacterium tuberculosis (TB), pregnancy is associated with an increased risk of developing or worsening TB disease. TB in pregnancy increases the risk of adverse maternal and neonatal outcomes; however, the detection of TB in pregnancy is challenging. We aimed to identify and summarise the findings of studies regarding the clinical presentation and diagnosis of TB during pregnancy and the postpartum period (within six months of birth) in low- and middle-income countries (LMICs).

Sero-prevalence and Risk Factors for Severe Acute Res ...

Room: 1.43-1.44 International Maternal Newborn Health Conference 2023 information@imnhc.org
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Mycoplasma Genitalium and Other Reproductive Tract Infections in Pregnancy Associated with an Increased Risk of Adverse Birth Outcomes in a High-Burden Setting

Being born too small is a major risk factor for neonatal and infant mortality and childhood stunting. Sexually transmitted infections (STIs) are preventable and curable infections that can contribute to poor pregnancy outcomes. Mycoplasma genitalium is increasingly recognized as an STI with high prevalence in some populations and has a high propensity to develop antimicrobial resistance. Little data are available on the impact of M. genitalium on adverse birth outcomes, particularly in the context of other STIs. In Papua New Guinea (PNG), we previously demonstrated a high burden of multiple STIs (M. genitalium, Chlamydia trachomatis, Neisseria gonorrhoeae, Trichomonas vaginalis, and bacterial vaginosis [BV]). Here, we have investigated the association between M. genitalium and other STIs and birthweight, preterm birth, and perinatal mortality.


The Clinical Presentation and Detection of Tuberculosis during Pregnancy and in the Postpartum Period in Low- and Middle-Income Countries: A Systematic Review and Meta-analysis 

For women infected with Mycobacterium tuberculosis (TB), pregnancy is associated with an increased risk of developing or worsening TB disease. TB in pregnancy increases the risk of adverse maternal and neonatal outcomes; however, the detection of TB in pregnancy is challenging. We aimed to identify and summarise the findings of studies regarding the clinical presentation and diagnosis of TB during pregnancy and the postpartum period (within six months of birth) in low- and middle-income countries (LMICs).


Sero-prevalence and Risk Factors for Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Women and Children in a Rural District of Bangladesh: A Cohort Study 

Bangladesh reported its first COVID-19 case on March 8, 2020. Despite lockdowns and promotion of behavioral interventions, as of December 31, 2021, Bangladesh had reported 1.5 million confirmed cases and 27,904 COVID-19-related deaths. To understand the course of the pandemic and identify risk factors for SARs-Cov-2 infection, we conducted a cohort study from November 2020 to December 2021 in rural Bangladesh.


Does the Continuous Presence of Mothers in a Newborn Intensive Care Unit to Provide Immediate Kangaroo Mother Care Increase Neonatal Sepsis? 

A multi-country randomized controlled trial conducted in five countries (India, Ghana, Tanzania, Nigeria, and Malawi), coordinated by the World Health Organization (WHO) (iKMC study), from November 2017 to January 2020 showed a 25% reduction in mortality by immediate kangaroo mother care (KMC) in neonates with birthweight 1 to 1.8 kg. This study was published in the New England Journal of Medicine (NEJM) (May 2021). To implement the immediate KMC intervention, mother and baby needed to be together continuously, which led to the concept of the "Mother–Newborn Care Unit (MNCU)." Health care providers and administrators were concerned about the potential increase in infections due to the presence of mothers/surrogates in the MNCU. We present a post hoc analysis of the iKMC study to see the effect of immediate KMC on neonatal sepsis.

Mycoplasma Genitalium and Other Reproductive Tract Infections in Pregnancy Associated with an Increased Risk of Adverse Birth Outcomes in a High-Burden Setting
Single Abstract 09:10 AM - 10:25 AM (Africa/Johannesburg) 2023/05/10 07:10:00 UTC - 2023/05/10 08:25:00 UTC
Small and Sick Newborns (SSNB)
Prevention and Clinical Management
Health Systems and Workforce
Presenters Michelle Scoullar
Senior Research Officer. Paediatrician., Burnet Institute
Co-authors
PB
Philippe Boeuf
Honorary Senior Research Officer , Burnet Institute
EP
Elizabeth Peach
Honorary, Burnet Institute
RF
Ruth Fidelis
Lab Manager, Burnet Institute
PM
Pele Melepia
Team Leader, Burnet Institute
CB
Catriona Bradshaw
Head Of Research Translation And Mentorship, Monash University
AE
Arthur Elijah
Senior Lecturer, University Of Papua New Guinea
AV
Andrew Vallely
Professor Global Reproductive Health, Kirby Institute
LV
Lisa Vallely
Senior Research Fellow, Kirby Institute
FF
Freya Fowkes
Deputy Director, Maternal Child And Adolescent Health Program, Burnet Institute
WP
William Pomat
Director, Papua New Guinea Institute Of Medical Research
BC
Brendan Crabb
CEO And Director, Burnet Institute
CM
Christopher Morgan
Senior Technical Advisor, Jhpiego, The Johns Hopkins University Affiliate
JB
James Beeson
Deputy Director, Burnet Institute
The Clinical Presentation and Detection of Tuberculosis during Pregnancy and in the Postpartum Period in Low- and Middle-Income Countries: A Systematic Review and Meta-analysis
Single Abstract 09:10 AM - 10:25 AM (Africa/Johannesburg) 2023/05/10 07:10:00 UTC - 2023/05/10 08:25:00 UTC
None
Prevention and Clinical Management
Humanitarian and Fragile Settings
Presenters Grace Simpson
Research Assistant, Burnet Institute
Co-authors
MP
Moira Philip
Volunteer, Burnet Institute
Joshua Vogel
Professor & Senior Principal Research Fellow, Burnet Institute
SG
Stephen Graham
Burnet Institute
AW
Alyce Wilson
Honorary Senior Research Fellow, Burnet Institute
Sero-prevalence and Risk Factors for Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Women and Children in a Rural District of Bangladesh: A Cohort Study
Single Abstract 09:10 AM - 10:25 AM (Africa/Johannesburg) 2023/05/10 07:10:00 UTC - 2023/05/10 08:25:00 UTC
COVID-19
Prevention and Clinical Management
Presenters Rasheda Khanam
Assistant Scientist, Johns Hopkins Bloomberg School Of Public Health
Co-authors
MI
Md. Shafiqul Islam
Data Analyst, Projahnmo Research Foundation
Mohammad Sayedur Rahman
Master's Student, Uppsala University
SA
Salahuddin Ahmed
Research Director, Projahnmo Research Foundation
ASMD Ashraful Islam
Project Manager, Projahnmo Research Foundation
TH
Tarik Hasan
Laboratory Officer, Projahnmo Research Foundation
EH
Emran Hasan
Research Investigator, Projahnmo Research Foundation
N
Nabidul Chowdhury
Data Manager, Projahnmo Research Foundation
AR
Arunangshu Roy
Deputy Research Director, Projahnmo Research Foundation
IJ
Iffat Jaben
Research Investigator, Projahnmo Research Foundation
AN
Asim Nehal
Assistant Data Manager, Projahnmo Research Foundation
SY
Sachiyo Yoshida
Technical Officer, Department Of Maternal, Newborn, Child And Adolescent Health And Ageing, World Health Organization
AM
Alexander Manu
Associate Professor, University Of Ghana School Of Public Health/London School Of Hygiene & Tropical Medicine
RR
Rubhana Raqib
Senior Scientist , International Center For Diarrheal Disease Research
EM
Eric McCollum
Associate Professor, Johns Hopkins University
AB
Abdullah Baqui
Professor, Johns Hopkins Bloomberg School Of Public Health
Does the Continuous Presence of Mothers in a Newborn Intensive Care Unit to Provide Immediate Kangaroo Mother Care Increase Neonatal Sepsis?
Single Abstract 09:10 AM - 10:25 AM (Africa/Johannesburg) 2023/05/10 07:10:00 UTC - 2023/05/10 08:25:00 UTC
Small and Sick Newborns (SSNB)
Prevention and Clinical Management
Strengthening Quality of Care
Presenters Harish Chellani
Professor, CHRD: Society For Applied Studies
Co-authors
SA
Sugandha Arya
Professor, VMMC & SAfdarjung Hospital
RB
Rajiv Bahl
Unit Head, World Health Organization
NW
Nitya Wadhwa
Translational Health Science And Technology Institute, Translational Health Science And Technology Institute
PA
Pratima Anand
Chief Medical Officer, Safdarjung Hospital
EA
Ebunoluwa Adejuyigbe
OBAFEMI AWOLOWO UNIVERSITY TEACHING HOSPITAL COMPLEX, OBAFEMI AWOLOWO UNIVERSITY TEACHING HOSPITAL COMPLEX
HN
Helga Naburi
Pediatrician, Muhimbili University Of Health And Allied Sciences, Dar Es Salaam, Tanzania
QD
Queen Dube
Chief Of Health Services, Ministry Of Health- Malawi
KK
Kondwani Kawaza
Associate Professor, Consultant Paediatrician And Neonatologist, Kamuzu University Of Health Sciences (KUHES)
SN
Samuel Newton
Dean School Of Public Health KWAME NKRUMAH UNIVERSITY OF SCIENCE AND TECHNOLOGY, KWAME NKRUMAH UNIVERSITY OF SCIENCE AND TECHNOLOGY
GP
Gyikua Phlange-Rhule
Pediatrician, School Of Medicine And Dentistry, Kwame Nkrumah University Of Science And Technology, Accra Road, Kumasi
SR
Siren Rettedal
Neonatologist, Professor, Stavanger University Hospital
NB
Nils Bergman
Neonatologist, Karolinska Institutet
SR
Suman Rao
Consultant , World Health Organization
Professor
,
CHRD: Society for Applied Studies
Assistant Scientist
,
Johns Hopkins Bloomberg School of Public Health
Research Assistant
,
Burnet Institute
Senior Research Officer. Paediatrician.
,
Burnet Institute
Dr. Swaraj Rajbhandari
Senior Consultant Ob/Gyn
,
Nidan Hospital, Nepal
Dr. Lisa Noguchi
Director, Maternal Newborn Health
,
Jhpiego
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The Clinical Presentation and Detection of Tube...
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Does the Continuous Presence of Mothers in a Ne...
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Sero-prevalence and Risk Factors for Severe Acu...
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Mycoplasma Genitalium and Other Reproductive Tr...
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